acetylcholine

Acetylcholine Category:health
The neurotransmitter substance at cholinergic synapses, which causes cardiac inhibition, vasodilation, gastrointestinal peristalsis, and other parasympathetic effects. It is liberated from preganglionic and postganglionic endings of parasympathetic fibers and from preganglionic fibers of the sympathetic as a result of nerve injuries, whereupon it acts as a transmitter on the effector organ; it is hydrolyzed into choline and acetic acid by acetylcholinesterase before a second impulse may be transmitted.








Acetylcholine Category:medicine
acetylcholine
<chemical, neurology, physiology> A chemical found in vertebrate neurons that carries information across the synaptic cleft, the space between two nerve cells.





acetylcholine
Ester of choline and acetic acid, a neurotransmitter active at many nerve synapses and at the motor end plate of vertebrate voluntary muscles
rnIt affects several of the body's systems, including the cardiovascular system (decreases heart rate and contraction strength, dilates blood vessels), gastrointestinal system (increases peristalsis in the stomach and amplitude of digestive contractions), and urinary system (decreases bladder capacity, increases voluntary voiding pressure). It also affects the respiratory system and stimulates secretion by all glands that receive parasympathetic nerve impulses (see autonomic nervous system). It is important in memory and learning and is deficient in the brains of those with late-stage Alzheimer disease
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